4-CMC (4-Chloromethcathinone) | Analytical Reference Standard

Are you seeking a verified, high-purity source for buy 4-CMC online in Europe? 4-CMC (4-chloromethcathinone), also known as Clephedrone, is a synthetic stimulant belonging to the substituted cathinone class. As a structural analog of mephedrone (4-MMC), it features a chlorine atom substitution at the para-position of the phenyl ring. Within the scientific community, it is a primary subject for researchers investigating the Structure-Activity Relationship (SAR) of halogenated stimulants and the development of high-resolution forensic detection assays.

We provide analytical-grade 4-CMC hydrochloride, verified via HPLC and GC-MS to ensure the $\geq$ 98% purity required for rigorous in vitro pharmacological investigations and toxicological studies.

Pharmacological Profile & Mechanism of Action

The addition of the chlorine atom at the 4-position significantly alters the electronic density and lipophilicity of the molecule. Researchers utilize 4-CMC to study:

Monoamine Transporter Affinity: Investigating the compound’s potency as a reuptake inhibitor and releasing agent for dopamine (DAT), norepinephrine (NET), and serotonin (SERT).
Halogenation Effects: Studying how the substitution of a methyl group (as in 4-MMC) with a chlorine atom influences the molecule’s metabolic stability and receptor residence time.
Neurotoxicological Profiles: Researching the impact of para-halogenated cathinones on neuronal integrity, drawing comparisons to the known effects of chlorinated amphetamines like p-chloroamphetamine (PCA).

Primary Research & Forensic Applications

Buy 4-CMC online in Europe is an essential reference material for several advanced scientific domains:

Forensic Toxicology: Serving as a validated reference standard (CAS: 122584-31-6) for LC-MS/MS and GC-MS libraries to identify and quantify novel psychoactive substances (NPS) in complex biological matrices.
Neuroscience Research: Exploring the modulation of neuronal signaling and the impact of 4-substituted cathinones on synaptic plasticity and serotonin system mapping.
Metabolic Mapping: Investigating the primary metabolic pathways of chlorinated cathinone analogs, specifically N-demethylation and the reduction of the ketone group.
Analytical Method Development: Calibrating sensitive equipment to ensure the accurate detection of synthetic stimulants in forensic and clinical settings.

Technical Specifications

Feature	Details
IUPAC Name	1-(4-chlorophenyl)-2-(methylamino)propan-1-one
CAS Number	122584-31-6
Molar Mass	197.66 g/mol (Base)
Purity Grade	Analytical Research Grade ( $\geq$ 98%)
Molecular Formula	$C_{10}H_{12}ClNO \cdot HCl$

Safety, Regulatory Status, and Procurement

4-CMC is intended strictly for laboratory research and is NOT for human or veterinary consumption.

Regulatory Compliance: Researchers must ensure procurement aligns with local jurisdictional laws. 4-CMC is controlled in many regions, including the EU and UK, under specific drug legislation or “analogue” acts.
Handling & PPE: Due to high physiological activity and potential neurotoxicity, the use of Personal Protective Equipment (PPE), including nitrile gloves, eye protection, and a fume hood, is mandatory.
Storage: To maintain chemical integrity, store in a cool, dry, and dark environment in airtight containers.

Why Source Through Licensed Distribution Channels?

Verified Analytical Integrity: Every batch is independently tested to ensure your research is conducted with materials of known concentration and high purity.
Professional Logistics: Secure, tracked shipping ensures that institutional research programs remain uninterrupted and compliant with regulatory requirements.
Technical Documentation: Orders are supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS).

Buy 4-CMC online in Europe

Advance your neuropharmacological and forensic investigations with certified 4-CMC. Contact our specialized distribution team today to secure high-purity materials for your facility... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .