3-CMC (3-Chloromethcathinone) | Analytical Reference Standard

Buy 3-CMC Powder Online In Europe| Premium Research Chemicals for laboratory use.

Are you seeking a verified, high-purity source for 3-CMC for laboratory use? 3-Chloromethcathinone, an analog of the naturally occurring alkaloid cathinone, is a potent stimulant of the phenethylamine class. Within the scientific community, it is a primary subject for researchers investigating monoamine transporter dynamics, the impact of halogenation on CNS activity, and the development of high-resolution forensic detection assays.

We provide analytical-grade 3-CMC Hydrochloride in high-surface-area powder format, verified via HPLC and LC-MS/MS to ensure the $\geq$98% purity required for rigorous in vitro pharmacological investigations and equipment calibration.

Pharmacological Profile & Mechanism of Action

3-CMC is utilized as a sophisticated chemical probe to study the structure-activity relationship (SAR) of halogen-substituted cathinones. Researchers utilize this compound to explore:

• Transporter Binding Affinity: Investigating its potency as a reuptake inhibitor at the Dopamine Transporter (DAT) and Serotonin Transporter (SERT).

• Positional Isomerism: Researching how the chlorine substitution at the meta (3-) position compares to the para (4-) position (4-CMC) in terms of metabolic stability and neurotoxicity.

• Catecholamine Release: Studying the compound’s ability to trigger the release of norepinephrine and dopamine into the synaptic cleft.

Primary Research & Forensic Applications

3-CMC Powder is an essential reference material for several advanced scientific domains:

• Forensic Toxicology: Serving as a validated reference standard (CAS: 1607439-32-6) for the identification of Novel Psychoactive Substances (NPS) in biological samples and seized materials.

• Metabolic Mapping: Investigating the enzymatic reduction of the beta-keto group to the corresponding alcohol (3-chlororephedrine/3-chloropseudosuphedrine) using S9 fractions.

• Analytical Method Development: Utilizing high-purity standards to calibrate GC-MS systems for the sensitive detection of substituted cathinones in environmental and clinical screenings.

• Neurotoxicity Research: Exploring the potential for oxidative stress and depletion of monoamine stores in neuronal cultures.

Technical Specifications

Safety, Regulatory Status, and Procurement

3-CMC is intended strictly for authorized laboratory research and is not for human consumption.

• Regulatory Compliance: 3-CMC is a regulated substance in the UK, the European Union, and several US jurisdictions. Procurement requires valid institutional licensing and adherence to ECHA and national narcotics laws.

• Handling & PPE: Due to its high physiological activity, the use of Personal Protective Equipment (PPE), including nitrile gloves and eye protection, is mandatory. Handle in a certified fume hood to avoid inhalation of fine particulates.

• Storage: Store in a cool, dry environment in airtight, light-resistant containers to prevent degradation.

Why Source Through Licensed Distribution Channels?

• Verified Analytical Integrity: Every batch is independently tested to ensure materials meet the rigorous standards required for peer-reviewed research.

• Chain of Custody: Professional logistics ensure tracked, secure shipping, maintaining the regulatory compliance required for institutional facilities.

• Technical Documentation: Orders supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS).

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Customer Support

At EliteChems, we are committed to providing exceptional customer service. If you have any questions regarding 3-CMC Powder or need assistance with your order, please reach out to us at support@elitechemscience.com.

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