3-CMC (3-Chloromethcathinone) | Analytical Reference Standard

Are you seeking a verified, high-purity source for buy 3-CMC online in Europe? 3-CMC (3-Chloromethcathinone), occasionally referred to in historical contexts by the colloquialism “Meow” (a term more traditionally associated with its 4-substituted analog, 4-MMC), is a synthetic stimulant of the substituted cathinone class. Within the scientific community, it is a primary subject for researchers investigating the Structure-Activity Relationship (SAR) of halogenated stimulants and the development of high-resolution forensic detection assays.

We provide analytical-grade 3-CMC hydrochloride, verified via HPLC and GC-MS to ensure the high chemical purity and molecular consistency required for rigorous in vitro pharmacological investigations and structural biology studies.

Pharmacological Profile & Mechanism of Action

Buy 3-CMC online in Europe, features a chlorine atom at the meta-position of the phenyl ring. Researchers utilize this compound to explore the biochemical markers of central nervous system (CNS) modulation:

Monoamine Transporter Affinity: Investigating the compound’s potency as a reuptake inhibitor and releasing agent for dopamine (DAT), norepinephrine (NET), and serotonin (SERT).
Positional Isomerism: Studying how the 3-position chlorine substitution alters the pharmacodynamics and neurotoxicity profile compared to its isomers, 2-CMC and 4-CMC.
Neurotoxicological Mapping: Researching the impact of halogenated cathinones on vesicular monoamine transporters and potential long-term alterations in neuronal signaling.

Primary Research & Forensic Applications

3-CMC is an essential reference material for several advanced scientific domains:

Neuroscience Research: Exploring the modulation of cortical circuits and the impact of substituted cathinones on extracellular neurotransmitter concentrations in laboratory models.
Forensic Toxicology: Serving as a validated reference standard (CAS: 1049677-59-9) for LC-MS/MS and GC-MS libraries to identify and quantify novel psychoactive substances (NPS).
Metabolic Studies: Investigating the primary metabolic pathways of chlorinated cathinones, including N-demethylation and the reduction of the ketone group to an alcohol.
Stability Testing: Utilizing 3-CMC to establish baseline data for the degradation of cathinone analogs under various environmental conditions.

Technical Specifications

Feature	Details
IUPAC Name	1-(3-chlorophenyl)-2-(methylamino)propan-1-one
CAS Number	1049677-59-9
Molar Mass	197.66 g/mol (Base)
Purity Grade	Analytical Research Grade ( $\geq$ 98%)
Molecular Formula	$C_{10}H_{12}ClNO \cdot HCl$

Safety, Regulatory Status, and Procurement

3-CMC is intended strictly for laboratory research and is NOT for human or veterinary consumption.

Regulatory Compliance: Researchers must ensure procurement aligns with local jurisdictional laws. Note that 3-CMC has been subject to increased regulation globally (including EU-wide bans in recent years); procurement is restricted to authorized institutional and academic facilities.
Handling & PPE: Due to high physiological activity, the use of Personal Protective Equipment (PPE), including nitrile gloves, eye protection, and a fume hood, is mandatory.
Storage: To maintain chemical integrity, store in a cool, dry, and dark environment in airtight containers.

Why Source Through Licensed Distribution Channels?

Verified Analytical Integrity: Every batch is independently tested to ensure your research is conducted with materials of known concentration and high purity.
Professional Logistics: We ensure secure, tracked shipping, maintaining the chain of custody required for institutional facilities.
Technical Documentation: Orders are supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS) for institutional safety compliance.

Buy 3-CMC online in Europe| Premium Research Chemicals

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