Buy Bromazolam Reference Standards Online | Certified Forensic Calibration Materials

Elite Chem Science delivers certified, high-purity Bromazolam analytical reference materials to support state forensic laboratories, clinical toxicology infrastructure, and international multi-analyte screening networks. As a heavily tracked designer triazolobenzodiazepine variant within modern novel psychoactive substance (NPS) monitoring systems, authenticated Bromazolam benchmarks are required to execute definitive quantitative profiles, calibrate sensitive detector modules, and eliminate false-positive anomalies across high-throughput screening assays.

Our reference materials are synthesized under strict laboratory workflows to preserve absolute batch-to-batch chemical uniformity. Each production lot undergoes extensive quality validation, securing complete traceability via high-field nuclear magnetic resonance (NMR) spectroscopy and gas chromatography-mass spectrometry (GC-MS) verification.

Advanced Chemical Profile & Mass Spectrometry Dynamics

Bromazolam (systematically cataloged as 8-bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine) is a synthetic triazolobenzodiazepine derivative. Structurally, it represents the direct bromine analogue of alprazolam, replacing the classic chlorine atom at the 8-position of the core benzodiazepine framework with an electron-dense bromine substituent.

This heavy halogenation significantly alters the molecule’s spatial configuration, electron affinity, and reverse-phase chromatographic migration behaviors. Under electrospray ionization positive mode (ESI+) conditions, Bromazolam displays a distinct isotopic cluster pattern due to the natural abundance distribution of bromine isotopes ( $^{79}\text{Br}$ and $^{81}\text{Br}$ ). This predictable mass split yields an unambiguous structural signature during liquid chromatography-tandem mass spectrometry (LC-MS/MS) multi-reaction monitoring runs, allowing analysts to differentiate it cleanly from chlorinated or fluorinated counterparts.

Technical Specifications Matrix

High-Velocity Target Parameter	Verified Analytical Specification Data
Systematic IUPAC Nomenclature	8-bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
CAS Registry Identifier	71368-80-4
Molecular Formula Block	$C_{17}H_{13}BrN_{4}$
Exact Monoisotopic Mass	352.0323 g/mol
Canonical SMILES String	CC1=NN=C2N1C3=C(C=C(C=C3)Br)C(=NC2)C4=CC=CC=C4
InChIKey Identifier	IQPQHCDVBCWJCD-UHFFFAOYSA-N
Purity Threshold Protocol	$\ge 98.0\%$ certified via definitive HPLC / Proton qNMR profiling
Regulatory Classification	Controlled Novel Psychoactive Substance (NPS) / Analytical Standard
Validated Solubility Profile	Soluble in Dimethyl Sulfoxide (DMSO), Dimethylformamide (DMF), and Chloroform

Mandatory Laboratory Safety & Compliance Proclamation Bromazolam is prepared exclusively as an analytical reference standard for laboratory research, forensic validation assays, and certified in vitro diagnostic processes. Due to strict scheduling updates and international drug monitoring frameworks, distribution is restricted strictly to licensed institutional accounts. This material is fundamentally not intended for human, clinical, therapeutic, or veterinary administration. All manipulation must proceed inside an authorized facility using verified containment hoods and standard personal protective equipment (PPE).

Frequently Asked Questions (FAQ)

What specific mass spectrometry transitions dictate Bromazolam identification?

In positive-mode electrospray ionization (ESI+), Bromazolam presents clear parent molecular ions $[M+H]^+$ at m/z 353.0 and 355.0, reflecting the characteristic bromine isotope profile. Collision-induced dissociation (CID) pathways generate primary, highly stable diagnostic product fragments at m/z 325.0 and m/z 205.0, which serve as foundational coordinates for multi-reaction monitoring (MRM) screening arrays.

How are Bromazolam reference standards stabilized against structural drift?

To protect the integrated triazole ring and prevent moisture-induced decomposition or oxidation over extended timelines, crystalline Bromazolam standards must be stored tightly sealed in their original amber vials inside a laboratory freezer maintained continuously at or below $-20^\circ\text{C}$ .

What verification documentation ships with an elite procurement lot?

Every batch distributed is supported by an immutable, lot-specific Certificate of Analysis (CoA). This official packet details the absolute purity verification profile, raw high-performance liquid chromatography (HPLC) traces, interpreted Proton NMR spectra, and a fully compliant Safety Data Sheet (SDS).