3-Me-PCE (3-Methyleticyclidine) | Analytical Reference Standard

Are you seeking a verified, high-purity source for Buy 3-Me-PCE online in Europe? 3-Me-PCE (3-methyleticyclidine) is a potent dissociative anesthetic of the arylcyclohexylamine class. It is the 3-methyl derivative of PCE (Eticyclidine) and a structural isomer of the more common 3-Me-PCP. Within the scientific community, it is a primary subject for researchers investigating the Structure-Activity Relationship (SAR) of N-ethylated arylcyclohexylamines and the impact of alkyl substitutions on the phenyl ring.

We provide analytical-grade 3-Me-PCE hydrochloride, verified via HPLC and LC-MS to ensure the $\geq$ 98% purity required for rigorous in vitro pharmacological investigations and structural biology studies.

Pharmacological Profile & Mechanism of Action

3-Me-PCE is utilized as a chemical probe to study the biochemical markers of central nervous system (CNS) modulation. Researchers utilize this compound to explore:

NMDA Receptor Antagonism: Acting as a high-affinity non-competitive antagonist at the N-methyl-D-aspartate (NMDA) receptor. It binds to the PCP site within the ion channel, modulating excitatory neurotransmission.
Monoamine Reuptake Inhibition: Researching its secondary activity as a reuptake inhibitor for dopamine and norepinephrine, contributing to its potential as a tool for studying monoaminergic signaling.
Structural Architecture: Characterized by an N-ethyl group and a 3-methyl substitution on the phenyl ring. Researchers study how this specific methylation influences lipid solubility and receptor residence time compared to 3-HO or 3-MeO analogs.

Primary Research & Forensic Applications

Buy 3-Me-PCE online in Europe is an essential reference material for several advanced scientific domains:

Neuroscience Research: Exploring the modulation of neuronal signaling and the impact of 3-position alkylation on the potency and selectivity of dissociative compounds.
Forensic Toxicology: Serving as a validated reference standard (CAS: 1354634-11-9) for LC-MS/MS and GC-MS libraries to identify and quantify novel psychoactive substances (NPS) in complex biological matrices.
Metabolic Mapping: Investigating the metabolic pathways of N-ethylated analogs, focusing on N-dealkylation and aryl-hydroxylation in in-vitro hepatic models.
Comparative Pharmacology: Utilizing 3-Me-PCE to differentiate the potency across the PCE-derivative family, providing baseline data for SAR modeling.

Technical Specifications

Feature	Details
IUPAC Name	N-ethyl-1-(3-methylphenyl)cyclohexan-1-amine
CAS Number	1354634-11-9
Molar Mass	217.35 g/mol (Base)
Purity Grade	Analytical Research Grade ( $\geq$ 98%)
Molecular Formula	$C_{15}H_{23}N \cdot HCl$

Safety, Regulatory Status, and Procurement

3-Me-PCE is intended strictly for laboratory research and is NOT for human or veterinary consumption.

Regulatory Compliance: Researchers must ensure procurement aligns with local jurisdictional laws regarding arylcyclohexylamines and “designer drug” analogues.
Handling & PPE: Due to high physiological activity at low milligram levels, the use of Personal Protective Equipment (PPE), including nitrile gloves, eye protection, and a fume hood, is mandatory.
Storage: To maintain maximum chemical integrity, store in a cool, dry, and dark environment in airtight containers.

Why Source Through Licensed Distribution Channels?

Verified Analytical Integrity: Every batch is independently tested to ensure your research is conducted with materials of known concentration and high purity.
Professional Logistics: Secure, tracked shipping ensures that institutional research programs remain uninterrupted and compliant with chain-of-custody requirements.
Technical Documentation: Orders are supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS).

Buy 3-Me-PCE online in Europe | Premium Research Chemicals

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