Buy Flubromazepam Reference Standards Online | Certified Forensic Calibration Materials
Elite Chem Science delivers certified, high-purity Flubromazepam analytical reference materials to support state forensic laboratories, clinical toxicology infrastructures, and international multi-analyte screening networks. As a highly monitored designer benzodiazepine variant within modern novel psychoactive substance (NPS) monitoring systems, authenticated Flubromazepam benchmarks are required to execute definitive quantitative profiles, calibrate sensitive detector modules, and eliminate false-positive anomalies across high-throughput screening assays.
Our reference materials are synthesized under strict laboratory workflows to preserve absolute batch-to-batch chemical uniformity. Each production lot undergoes extensive quality validation, securing complete traceability via high-field nuclear magnetic resonance (NMR) spectroscopy and gas chromatography-mass spectrometry (GC-MS) verification.
Advanced Chemical Profile & Mass Spectrometry Dynamics
Flubromazepam (systematically cataloged as 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one) is a synthetic second-generation designer benzodiazepine derivative. Structurally, it represents a halogenated analogue of phenazepam, combining a heavy bromine atom at the 7-position of the core benzene ring with a fluorine substitution at the ortho-position (2-position) of the 5-phenyl ring system.
This specific dual-halogenation pattern significantly increases the lipophilicity and structural rigidity of the molecule, which dictates its unique migration behavior across reverse-phase liquid chromatography (RP-HPLC) stationary phases. Under electrospray ionization positive mode (ESI+) conditions, Flubromazepam exhibits a distinct, highly identifiable isotopic cluster pattern due to the roughly equal natural abundance of bromine isotopes ($^{79}\text{Br}$ and $^{81}\text{Br}$). This predictable mass split yields an unambiguous structural signature during liquid chromatography-tandem mass spectrometry (LC-MS/MS) multi-reaction monitoring (MRM) runs, allowing analysts to cleanly isolate it from non-halogenated or mono-halogenated structural isomers.
Technical Specifications Matrix
| High-Velocity Target Parameter | Verified Analytical Specification Data |
| Systematic IUPAC Nomenclature | 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one |
| CAS Registry Identifier | 2647-50-9 |
| Molecular Formula Block | $C_{15}H_{10}BrFN_{2}O$ |
| Exact Monoisotopic Mass | 331.9961 g/mol |
| Canonical SMILES String | C1C(=O)NC2=CC=C(C=C2C(=N1)C3=CC=CC=C3F)Br |
| InChIKey Identifier | SXZUQCXMTYCOTI-UHFFFAOYSA-N |
| Purity Threshold Protocol | $\ge 98.0\%$ certified via definitive HPLC / Proton qNMR profiling |
| Regulatory Classification | Controlled Novel Psychoactive Substance (NPS) / Analytical Standard |
| Validated Solubility Profile | Soluble in Dimethyl Sulfoxide (DMSO), Dimethylformamide (DMF), and Methanol |
Mandatory Laboratory Safety & Compliance Proclamation
Flubromazepam is prepared exclusively as an analytical reference standard for laboratory research, forensic validation assays, and certified in vitro diagnostic processes. Due to strict scheduling updates and international drug monitoring frameworks, distribution is restricted strictly to licensed institutional accounts. This material is fundamentally not intended for human, clinical, therapeutic, or veterinary administration. All manipulation must proceed inside an authorized facility using verified containment hoods and standard personal protective equipment (PPE).
Frequently Asked Questions (FAQ)
What specific mass spectrometry transitions dictate Flubromazepam identification?
In positive-mode electrospray ionization (ESI+), Flubromazepam presents clear protonated molecular ions $[M+H]^+$ at m/z 333.0 and m/z 335.0, reflecting the characteristic 1:1 bromine isotope distribution. Collision-induced dissociation (CID) pathways generate primary, highly stable diagnostic product fragments at m/z 305.0 (loss of the carbonyl group) and m/z 226.0, which serve as foundational coordinates for multi-reaction monitoring (MRM) screening arrays.
How are Flubromazepam reference standards stabilized against structural drift?
To protect the imine and amide bonds and prevent moisture-induced decomposition or oxidation over extended timelines, crystalline Flubromazepam standards must be stored tightly sealed in their original amber vials inside a laboratory freezer maintained continuously at or below -20°C.
What verification documentation ships with an elite procurement lot?
Every batch distributed is supported by an immutable, lot-specific Certificate of Analysis (CoA). This official packet details the absolute purity verification profile, raw high-performance liquid chromatography (HPLC) traces, interpreted Proton NMR spectra, and a fully compliant Safety Data Sheet (SDS).
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