3-Me-PCP (3-Methylphencyclidine) | Analytical Reference Standard

Are you seeking a verified, high-purity source for buy 3-Me-PCP online in Europe? 3-Me-PCP (3-methylphencyclidine) is a potent dissociative anesthetic belonging to the arylcyclohexylamine class. It is a structural analog of PCP, characterized by a methyl group substitution at the meta-position of the phenyl ring. Within the scientific community, it is a primary subject for researchers investigating the Structure-Activity Relationship (SAR) of aminergic GPCRs and the development of high-resolution forensic detection assays.

We provide analytical-grade 3-Me-PCP hydrochloride, verified via HPLC and LC-MS to ensure the $\geq$ 98% purity required for rigorous in vitro pharmacological investigations and structural biology studies.

Pharmacological Profile & Mechanism of Action

3-Me-PCP is utilized as a chemical probe to study the biochemical markers of central nervous system (CNS) modulation. Researchers utilize this compound to explore:

NMDA Receptor Antagonism: Acting as a high-affinity non-competitive antagonist at the N-methyl-D-aspartate (NMDA) receptor. It binds to the PCP site within the ion channel, modulating excitatory neurotransmission.
Monoamine Reuptake Inhibition: Researching its potency as an inhibitor for the dopamine transporter (DAT) and norepinephrine transporter (NET), contributing to its distinct stimulatory and dissociative profile.
Structural Architecture: The 3-methyl substitution is studied for its impact on the molecule’s lipophilicity and its ability to cross the blood-brain barrier compared to unsubstituted PCP or 3-MeO-PCP.

Primary Research & Forensic Applications

buy 3-Me-PCP online in Europe is an essential reference material for several advanced scientific domains:

Neuroscience Research: Exploring the modulation of neuronal signaling and the impact of 3-position alkylation on the potency and selectivity of dissociative compounds.
Forensic Toxicology: Serving as a validated reference standard (CAS: 1622348-63-3) for LC-MS/MS and GC-MS libraries to identify and quantify novel psychoactive substances (NPS) in complex biological matrices.
Structure-Activity Relationship (SAR) Mapping: Utilizing 3-Me-PCP as a probe to understand how steric changes on the aromatic ring alter binding kinetics at the NMDA receptor.
Metabolic Mapping: Investigating the metabolic pathways of methylated PCP analogs, specifically the hydroxylation of the cyclohexyl and phenyl rings.

Technical Specifications

Feature	Details
IUPAC Name	1-[1-(3-methylphenyl)cyclohexyl]piperidine
CAS Number	1622348-63-3
Molar Mass	257.41 g/mol (Base)
Purity Grade	Analytical Research Grade ( $\geq$ 98%)
Molecular Formula	$C_{18}H_{27}N \cdot HCl$

Safety, Regulatory Status, and Procurement

3-Me-PCP is intended strictly for laboratory research and is NOT for human or veterinary consumption.

Regulatory Compliance: Researchers must ensure procurement aligns with local jurisdictional laws regarding PCP analogs. In many regions, 3-Me-PCP is controlled under “analogue” or “designer drug” legislation.
Handling & PPE: Due to extreme physiological activity at low milligram levels, the use of Personal Protective Equipment (PPE), including nitrile gloves, eye protection, and a fume hood, is mandatory.
Storage: To maintain maximum molecular stability, store in a cool, dry, and dark environment in airtight containers.

Why Source Through Licensed Distribution Channels?

Verified Analytical Integrity: Every batch is independently tested to ensure your research is conducted with materials of known concentration and high purity.
Chain of Custody: Professional logistics ensure tracked, secure shipping, maintaining the compliance required for institutional and academic facilities.
Technical Documentation: Orders are supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS).

Buy 3-Me-PCP online in Europe | Premium Research Chemicals

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