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2C-B-FLY | Analytical Reference Standard for Serotonergic Research


Are you seeking a verified, high-purity source for Buy 2C-B-FLY online in Europe? 2C-B-FLY (8-bromo-2,3,6,7-benzo[1,2-b:4,5-b’]difuran-4-ethylamine) is a potent psychoactive molecule belonging to the phenethylamine and benzodifuran classes. Within the scientific community, it is a primary subject for researchers investigating the impact of rigidified structure on the pharmacodynamics of phenethylamines and the development of high-affinity ligands for $5\text{-HT}_{2}$ receptor mapping.

We provide analytical-grade 2C-B-FLY hydrochloride, verified via HPLC and GC-MS to ensure the $\geq$98% purity required for consistent results in neurobiological and toxicological studies.


Pharmacological Profile & Mechanism of Action

2C-B-FLY for say Poland is distinguished by its unique “fly” structure, where the methoxy groups of 2C-B are incorporated into dihydrobenzofuran rings. Researchers utilize this compound to study:

  • Rigidified Conformation: Studying how the restricted rotation of the oxygen atoms—locked into the benzodifuran rings—dramatically increases binding affinity compared to flexible phenethylamines.

  • Serotonergic Agonism: Primarily acting as a high-affinity partial agonist at the $5\text{-HT}_{2\text{A}}$ receptor, as well as showing significant activity at the $5\text{-HT}_{2\text{B}}$ and $5\text{-HT}_{2\text{C}}$ subtypes.

  • Binding Kinetics: Investigating the prolonged duration of action and receptor-ligand residence times, which are central to understanding the biochemical markers of sensory perception.


Primary Research & Forensic Applications

2C-B-FLY is an essential tool for several advanced scientific domains:

  • Neuroscience Research: Exploring the modulation of cortical circuits and the impact of rigidified phenethylamine analogs on neuronal plasticity.

  • Forensic Toxicology: Serving as a validated reference standard (CAS: 178557-21-6) for LC-MS/MS and GC-MS libraries to identify substituted benzodifurans in complex biological matrices.

  • Structure-Activity Relationship (SAR) Mapping: Utilizing 2C-B-FLY as a probe to understand the structural requirements for maximal efficacy at aminergic GPCRs.

  • Metabolic Profiling: Investigating the metabolic pathways of benzodifurans, focusing on O-dealkylation and oxidative deamination.


Technical Specifications

Feature Details
IUPAC Name 2-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b’]difuran-4-yl)ethanamine
CAS Number 178557-21-6
Molar Mass 284.15 g/mol (Base)
Purity Grade Analytical Research Grade ($\geq$98%)
Molecular Formula $C_{12}H_{14}BrNO_{2} \cdot HCl$

Safety, Regulatory Status, and Procurement

2C-B-FLY is strictly for laboratory research and is NOT for human or veterinary consumption.

  • EU Regulatory Notice (2026): Researchers must ensure compliance with current local and EU-wide regulations regarding substituted phenethylamines. Procurement is restricted to facilities with appropriate authorization for handling investigational compounds.

  • Handling & PPE: Due to its high physiological activity at low milligram levels, the use of Personal Protective Equipment (PPE), including nitrile gloves, eye protection, and a fume hood, is mandatory.

  • Storage: Maintain maximum chemical stability by storing in a cool, dry, and dark environment (preferably $4\degree\text{C}$ or below) in airtight containers.


Why Source Through Licensed Distribution Channels?

  • Verified Analytical Integrity: Every batch is independently tested to ensure your research is conducted with materials of known concentration and high purity.

  • Logistical Security: We offer secure, tracked shipping across the EU, ensuring that institutional research timelines remain uninterrupted and compliant.

  • Technical Documentation: Orders are supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS) for institutional safety audits.


    Buy 2C-B-FLY online in Europe | Research Chemicals For Sale

Advance your psychopharmacological and neurochemical investigations with certified 2C-B-FLY for sale Europe. Contact our specialized distribution team today to secure high-purity materials for your facility.