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1cP-MiPLA (1-Cyclopropionyl-MiPLA) | Analytical Reference Standard for Lysergamide Research

Are you seeking a verified, high-purity source for buy 1cP-MiPLA online in Europe? 1cP-MiPLA (1-cyclopropionyl-N-methyl-N-isopropyllysergamide) is a novel analog of MiPLA and a structural derivative of the lysergamide family. Within the global scientific community, it is a primary subject for researchers investigating how N1-cyclopropionyl substitution and N-alkyl modifications influence receptor-ligand kinetics, metabolic pathways, and the development of high-resolution forensic screening assays.

We provide analytical-grade 1cP-MiPLA for sale Netherlands, verified via HPLC and LC-MS to ensure the high chemical purity and molecular consistency required for rigorous in vitro pharmacological investigations and structural biology studies.


Pharmacological Profile & Mechanism of Action

1cP-MiPLA Europe is a member of the “1-substituted” lysergamides, utilized by researchers to explore the biochemical markers of central nervous system (CNS) modulation and the influence of sterically diverse N-substituents:

  • N-Alkyl Chain Analysis: Unlike LSD, which features an N,N-diethyl substitution, MiPLA analogs utilize N-methyl-N-isopropyl groups. Researchers study 1cP-MiPLA to determine how these changes alter binding orientation within the $5\text{-HT}_{2\text{A}}$ receptor pocket.

  • Prodrug Mapping: Investigating the enzymatic hydrolysis of the cyclopropionyl group at the N1 position and its role in modulating the compound’s bioavailability and onset of action in laboratory models.

  • Serotonergic Selectivity: Mapping the compound’s affinity across the serotonin receptor sub-families ($5\text{-HT}_{1\text{A}}$, $5\text{-HT}_{2\text{A}}$, $5\text{-HT}_{2\text{C}}$) to establish comparative neurochemical profiles.


Primary Research & Forensic Applications

1cP-MiPLA is an essential reference material for several advanced scientific domains:

  • Neurochemical Research: Exploring the modulation of neuronal signaling and the impact of N-alkyl substitutions on the ergoline backbone.

  • Forensic Toxicology: Serving as a validated reference standard for LC-MS/MS and GC-MS libraries to assist laboratories in the identification and quantification of novel lysergamide analogs.

  • Structure-Activity Relationship (SAR) Mapping: Utilizing 1cP-MiPLA as a probe to understand the structural requirements for high-affinity ligand binding at aminergic GPCRs.

  • Metabolic Studies: Evaluating the pharmacokinetics and metabolic stability of acylated lysergamides in controlled in-vitro hepatic models.


Technical Specifications

Feature Details
IUPAC Name (8$\beta$)-1-cyclopropanecarbonyl-N-isopropyl-N,6-dimethyl-9,10-didehydroergoline-8-carboxamide
Chemical Class Lysergamide
Purity Grade Analytical Research Grade ($\geq$98%)
Verification HPLC, LC-MS, and NMR Verified
Molecular Formula $C_{24}H_{29}N_{3}O_{2}$

Safety, Regulatory Status, and Global Procurement

1cP-MiPLA is intended strictly for laboratory research and is NOT for human or veterinary consumption.

  • Licensed & Registered Supplier: As a globally recognized distributor, elitechems ensures that all procurement follows strict international regulatory frameworks and institutional safety requirements.

  • Handling & PPE: Due to high physiological activity, the use of Personal Protective Equipment (PPE), including nitrile gloves and eye protection, is mandatory. All handling should occur within a professional laboratory environment.

  • Storage: To maintain maximum molecular stability, store 1cP-MiPLA in a cool, dry, and dark environment (preferably at $-20\degree\text{C}$ for long-term preservation) in airtight containers.


Why Global Researchers Choose Elitechems

  • Laboratory-Verified Integrity: Every batch is independently tested to ensure the research-grade quality demanded by pharmaceutical labs and academic institutions.

  • Secure Global Logistics: Reliable international shipping to Europe, North America, and Asia, with discreet packaging and comprehensive compliance monitoring.

  • Professional Documentation: Each order is supported by batch-specific analytical data and Safety Data Sheets (SDS) to ensure seamless integration into institutional workflows.


Buy 1cP-MiPLA online in Europe

Advance your psychopharmacological and neurochemical investigations with certified 1cP-MiPLA. Contact the Elitechems team today to secure high-purity reference materials for your facility.

Price range: € 43,30 through € 515,00