3F-α-PVP (3-Fluoro-α-pyrrolidinopentiophenone) | Analytical Reference Standard

Are you seeking a verified, high-purity source for buy 3F-α-PVP online in Europe? 3-Fluoro-α-pyrrolidinopentiophenone is a synthetic stimulant of the pyrrolidinophenone class, featuring a fluorine substitution at the meta-position of the phenyl ring. As a structural analog of the potent dopamine transporter inhibitor α-PVP, this compound is a primary subject for researchers investigating the Structure-Activity Relationship (SAR) of fluorinated stimulants and the development of high-resolution forensic detection assays.

We provide analytical-grade 3F-α-PVP hydrochloride, verified via HPLC and GC-MS to ensure the $\geq$ 98% purity required for rigorous in vitro pharmacological investigations and toxicological study.

Pharmacological Profile & Mechanism of Action

The addition of the fluorine atom at the 3-position significantly alters the electronic density of the phenyl ring, affecting its metabolic stability and receptor affinity. Researchers utilize 3F-α-PVP to study:

DAT/NET Inhibition: Investigating the compound’s potency as a potent reuptake inhibitor of the dopamine transporter (DAT) and norepinephrine transporter (NET).
Fluorination Effects: Studying how the high electronegativity of fluorine influences the molecule’s lipophilicity and its ability to cross the blood-brain barrier compared to α-PVP or 4F-α-PVP.
Pyrrolidine Ring Dynamics: Exploring the impact of the pyrrolidine moiety on the binding kinetics and residence time at the transporter site.

Primary Research & Forensic Applications

Buy 3F-α-PVP online in Europe is an essential reference material for several advanced scientific domains:

Forensic Toxicology: Serving as a validated reference standard (CAS: 1246816-62-5 or related isomers) for LC-MS/MS and GC-MS libraries to identify and quantify novel psychoactive substances (NPS) in complex biological matrices.
Neuroscience Research: Exploring the impact of potent pyrrolidinophenones on extracellular neurotransmitter concentrations and potential neurotoxicological profiles.
Metabolic Mapping: Investigating the primary metabolic pathways of fluorinated cathinone analogs, focusing on the oxidation of the pyrrolidine ring and the reduction of the ketone group.
Isomeric Differentiation: Utilizing 3F-α-PVP as a comparative standard to distinguish meta-substituted isomers from their para-substituted (4-fluoro) counterparts during analytical testing.

Technical Specifications

Feature	Details
IUPAC Name	1-(3-fluorophenyl)-2-(pyrrolidin-1-yl)pentan-1-one
Chemical Class	Substituted Pyrrolidinophenone
Molar Mass	249.32 g/mol (Base)
Purity Grade	Analytical Research Grade ( $\geq$ 98%)
Molecular Formula	$C_{15}H_{20}FNO \cdot HCl$

Safety, Regulatory Status, and Procurement

3F-α-PVP is intended strictly for laboratory research and is NOT for human or veterinary consumption.

Regulatory Compliance: Researchers must ensure procurement aligns with local jurisdictional laws regarding substituted cathinones and pyrrolidinophenones. 3F-α-PVP is frequently subject to “analogue” legislation or NPS bans.
Handling & PPE: Due to extreme physiological activity and high potency, the use of Personal Protective Equipment (PPE), including nitrile gloves, eye protection, and a fume hood, is mandatory.
Storage: To maintain chemical integrity, store in a cool, dry, and dark environment in airtight containers.

Why Source Through Licensed Distribution Channels?

Verified Analytical Integrity: Every batch is independently tested to ensure your research is conducted with materials of known concentration and high purity.
Professional Logistics: Secure, tracked shipping ensures that institutional research programs remain uninterrupted and compliant with regulatory requirements.
Technical Documentation: Orders are supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS) for institutional safety audits.

Buy 3F-α-PVP online in Europe | elitechemscience.com

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