Buy GW501516 (Cardarine) Reference Standards Online | Certified Purity

Elite Chem Science supplies certified, ultra-pure GW501516 (Cardarine) reference materials to support academic research institutions, clinical chemistry laboratories, and anti-doping monitoring networks worldwide. As the premier investigative tool for studying peroxisome proliferator-activated receptor delta (PPARδ) pathways, high-purity GW501516 is a critical target analyte for verifying metabolic shifts, tracking experimental biomarker adaptations, and establishing definitive forensic toxicological baselines.

Our GW501516 reference standards are engineered under rigorous laboratory quality controls to guarantee absolute batch-to-batch chemical uniformity. Each lot undergoes absolute characterization using high-field nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GC-MS), and high-performance liquid chromatography (HPLC) to ensure complete data integrity across your testing pipelines.

Chemical Profile & Structural Classification

GW501516 (systematically designated as 2-[4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methyl]sulfanyl]-2-methylphenoxy]acetic acid) is a synthetic selective PPARδ receptor agonist. Structurally, it features a highly distinctive architecture combining a central 1,3-thiazole ring system linked via a thioether bridge to a substituted phenoxyacetic acid core. The opposite side of the thiazole ring is substituted with a phenyl group heavily modified by a terminal trifluoromethyl group.

This structural design grants the molecule high lipophilicity and a unique electronic configuration. The combination of the sulfur-containing thiazole ring, the thioether link, and the strong electron-withdrawing fluorines results in highly specific fragmentation pathways under mass spectrometry and unique retention metrics in liquid chromatography. Because it completely lacks the standard steroid backbone or phenethylamine structure, having a certified, highly authenticated reference matrix is essential for correctly identifying the compound and avoiding misinterpretations in automated multi-analyte toxicological screenings.

GW501516 Technical Specifications

Technical Parameter	Specification / Detail
Systematic IUPAC Name	2-[4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methyl]sulfanyl]-2-methylphenoxy]acetic acid
Common Synonyms	Cardarine, Endurobol, GW1516, GSK-516
CAS Registry Number	317318-73-0
Chemical Classification	PPARδ Agonist / Metabolic Modulator
Molecular Formula	$C_{21}H_{18}F_{3}NO_{3}S_{2}$
Molar Mass	453.50 g/mol
Available Form	High-purity crystalline solid / analytical reference powder
Purity Threshold	≥ 98.0% verified via definitive HPLC / NMR validation
Solubility Profile	Soluble in DMSO (up to 25 mg/mL), Ethanol (up to 15 mg/mL), and DMF

Mandatory Laboratory Safety & Regulatory Notice GW501516 (Cardarine) is classified strictly as an investigational research chemical and analytical reference standard. It is listed on the World Anti-Doping Agency (WADA) Prohibited List under Category S4 (Hormone and Metabolic Modulators) and is strictly banned from competitive sports globally. This material is synthesized solely for in vitro laboratory evaluations, cellular metabolic tracking, and forensic validation assays. It is absolutely not intended for human, clinical, therapeutic, or veterinary administration. Handling must occur in an approved facility with proper personal protective equipment (PPE).

Frequently Asked Questions (FAQ)

What specific analytical markers identify GW501516 during LC-MS/MS testing? In electrospray ionization positive mode (ESI+), GW501516 cleanly produces a prominent protonated molecular ion $[M+H]^+$ at m/z 454.1. Under collision-induced dissociation (CID), it yields highly specific diagnostic product ions—most notably at m/z 257.0 (representing the trifluoromethylphenyl-methylthiazole fragment) and m/z 197.1, allowing precise quantification and unambiguous differentiation from other experimental metabolic modulators.

How should GW501516 reference standards be stored to maximize shelf life? To protect the thioether link from ambient oxidation and safeguard the solid matrix against crystalline moisture pull, GW501516 powder must be stored in a secure laboratory freezer maintained at or below -20°C. Ensure the container remains tightly sealed, dry, and protected from direct UV light exposure.

What documentation accompanies an Elite Chem Science GW501516 shipment? Every reference standard delivered by Elite Chem Science is backed by an exhaustive, lot-specific quality assurance profile. This includes a comprehensive Certificate of Analysis (CoA) documenting high-field Proton NMR spectra, high-resolution mass spectrometry validation data logs, and an operational Safety Data Sheet (SDS).