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Buy DOC Reference Standards Online | Certified Phenethylamine Standards


Elite Chem Science supplies certified, high-purity DOC (2,5-Dimethoxy-4-chloroamphetamine) reference materials to support forensic analysis registries, clinical toxicology frameworks, and academic research into substituted phenethylamines. As a potent member of the halogenated amphetamine (DOx) class, DOC serves as a vital target analyte in consumer safety screening networks, helping analytical laboratories differentiate closely related structural analogues during high-resolution screening.

Our DOC reference standards are engineered to meet strict quality control parameters, ensuring unmatched lot-to-lot chemical uniformity. Every batch undergoes rigorous characterization to guarantee repeatable baseline calibrations across gas chromatography-mass spectrometry (GC-MS) platforms and liquid chromatography-tandem mass spectrometry (LC-MS/MS) validation workflows.

Chemical Profile & Structural Classification

DOC (systematically designated as 1-(4-chloro-2,5-dimethoxyphenyl)propan-2-amine) is a synthetic molecule belonging to the phenethylamine and phenylisopropylamine chemical families. Structurally, it features a core amphetamine backbone with methoxy functional groups located at the C2 and C5 positions of the phenyl ring. The distinguishing feature of DOC is the targeted insertion of a chlorine atom at the C4 position.

This specific halogenated structure substantially modifies the molecule’s overall electron density and molecular profile. In analytical environments, this chlorine group gives rise to a distinct isotopic fragmentation pattern (showing the characteristic $M^+$ and $M+2$ mass peak ratio due to chlorine isotopes) and specific chromatographic retention properties. These unique metrics allow toxicologists to confidently isolate and differentiate DOC from closely related substitutes like DOB, DOM, or DOI.

DOC Technical Specifications

Technical Parameter Specification / Detail
Systematic IUPAC Name 1-(4-chloro-2,5-dimethoxyphenyl)propan-2-amine
Common Synonyms 2,5-Dimethoxy-4-chloroamphetamine, 4-chloro-2,5-DMA, DOC
CAS Registry Number 123431-31-2 (Free Base) | 42203-77-0 (HCl Salt)
Chemical Classification Substituted Amphetamine / Halogenated Phenethylamine
Molecular Formula $C_{11}H_{16}ClNO_2 \cdot HCl$ (Hydrochloride salt)
Molar Mass 266.16 g/mol (HCl Salt) | 229.70 g/mol (Free Base)
Available Form High-purity crystalline powder / certified reference solution matrix
Purity Threshold $\ge 98.0\%$ verified via comprehensive analytical profiling

Mandatory Regulatory & Global Control Notice

2,5-Dimethoxy-4-chloroamphetamine (DOC) is classified globally under Schedule I of the 1971 UN Convention on Psychotropic Substances. This material is synthesized exclusively as an analytical reference standard and laboratory reagent for in vitro testing, forensic profiling, and authorized institutional research. It is entirely prohibited for human, medical, or veterinary administration. Orders can only be fulfilled for verified institutions providing active credentials, such as regional controlled substance permits, valid DEA registrations, or certified international import licenses.

Frequently Asked Questions (FAQ)

What spectral traits identify DOC during mass spectrometry?

Under electron ionization mass spectrometry (EI-MS), the chlorine atom at the 4-position causes a visible isotopic split of 2 mass units (representing $^{35}\text{Cl}$ and $^{37}\text{Cl}$ isotopes) within the parent ion fragment pool. This signature, along with its specific amine-cleavage fragment profiles, provides a definitive baseline to separate DOC from non-halogenated designator structures.

What certification documents accompany an Elite Chem Science DOC shipment?

Every reference standard shipped is backed by an exhaustive quality assurance package. This documentation includes a batch-specific Certificate of Analysis (CoA) containing authentic high-field Proton NMR ($^1\text{H-NMR}$) data, High-Performance Liquid Chromatography (HPLC) purity charts, and an operational Safety Data Sheet (SDS) explaining secure handling regulations.

What are the ideal long-term storage requirements for DOC analytical standards?

To preserve structural stability and prevent moisture absorption, store DOC hydrochloride inside a secure laboratory freezer at or below $-20^\circ\text{C}$. Keep the container tightly sealed, away from direct UV exposure, open heat sources, and aggressive ambient atmospheres.

Request an Institutional Bulk Quote

Maintain absolute data integrity throughout your laboratory’s screening pipelines. Request a custom bulk quotation via Elite Chem Science’s secure institutional portal.

Price range: € 49,75 through € 439,50
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