3-CMC (3-Chloromethcathinone) | Analytical Reference Standard
Buy 3-CMC Online In Europe for laboratory use
Are you seeking a verified, high-purity source for Buy 3-CMC Online In Europe for laboratory use? 3-Chloromethcathinone, a member of the substituted cathinone family, is a chlorinated analog of methcathinone. Within the scientific community, it is a primary subject for researchers investigating monoamine transporter kinetics, structural biology, and the development of high-resolution forensic detection assays.
We provide analytical-grade 3-CMC Hydrochloride for sale in crystal and powder formats, verified via HPLC and LC-MS/MS to ensure the $\geq$98% purity required for rigorous in vitro pharmacological investigations and equipment calibration.
Pharmacological Profile & Mechanism of Action
3-CMC is utilized as a sophisticated chemical probe to study the impact of halogen substitution on phenethylamine derivatives. Researchers utilize this compound to explore:
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Monoamine Reuptake Inhibition: Investigating its affinity for the Dopamine Transporter (DAT) and Serotonin Transporter (SERT). It is often compared to its isomer, 4-CMC, to determine positional isomerism’s effect on receptor selectivity.
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Substrate-Mediated Release: Studying its potential role as a monoamine releaser and its impact on the reversal of transporter flux.
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Neurochemical Signaling: Researching the modulation of extracellular catecholamine levels in various neuronal cell line models.
Primary Research & Forensic Applications
3-CMC is an essential reference material for several advanced scientific domains:
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Forensic Toxicology: Serving as a validated reference standard (CAS: 1607439-32-6) for identifying and quantifying Novel Psychoactive Substances (NPS) in complex biological matrices.
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Isomeric Differentiation: Utilizing high-purity standards to establish analytical methods (e.g., specific GC-MS fragmentation patterns) to distinguish 3-CMC from 2-CMC or 4-CMC.
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Metabolic Mapping: Investigating the enzymatic N-dealkylation and ketone reduction pathways using hepatic microsomal models.
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Neurotoxicity Assessments: Exploring the in vitro cytotoxic effects of halogenated cathinones on dopaminergic and serotonergic neurons.
Technical Specifications
| Feature | Details |
| IUPAC Name | 1-(3-chlorophenyl)-2-(methylamino)propan-1-one |
| CAS Number | 1607439-32-6 (HCl) / 827-27-0 (Base) |
| Molar Mass | 197.66 g/mol (Base) / 234.12 g/mol (HCl) |
| Purity Grade | Analytical Reference Grade ($\geq$98%) |
| Molecular Formula | $C_{10}H_{12}ClNO \cdot HCl$ |
Safety, Regulatory Status, and Procurement
3-CMC is intended strictly for authorized laboratory research and is not for human consumption.
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Regulatory Compliance: 3-CMC is a controlled substance in many jurisdictions (including the EU and various US states). Procurement requires valid institutional licensing and adherence to ECHA and national narcotics laws.
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Handling & PPE: Due to its high physiological activity, the use of Personal Protective Equipment (PPE), including nitrile gloves, eye protection, and a certified fume hood, is mandatory.
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Storage: Store in a cool, dry environment in airtight, light-resistant containers to ensure long-term molecular stability and prevent hygroscopic degradation.
Why Source Through Licensed Distribution Channels?
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Verified Analytical Integrity: Every batch is independently tested to ensure materials meet the rigorous standards required for peer-reviewed research.
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Chain of Custody: Professional logistics ensure tracked, secure shipping, maintaining the regulatory compliance required for institutional facilities.
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Technical Documentation: Orders supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS).
Buy 3-CMC Online In Europe | Premium Research Chemicals
Advance your neuropharmacological and forensic investigations with certified 3-CMC standards. Contact our specialized distribution team today to secure high-purity materials for your facility.
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