Buy 3-Me-PCE Powder (3-Methyleticyclidine) | Premium Research Chemical For Sale
Are you investigating the structure-activity relationships of methylated arylcyclohexylamines? 3-Me-PCE Powder (3-Methyleticyclidine) is a potent synthetic research chemical and a structural analogue of eticyclidine (PCE). It features a methyl group at the 3-position of the phenyl ring, a specific modification that researchers study to determine its influence on receptor binding kinetics and metabolic pathways compared to 3-MeO or 3-HO substitutions.
For institutions looking to buy research chemicals online, sourcing 3-Me-PCE in a high-purity powder form is vital for the preparation of standardized solutions used in in vitro assays and controlled behavioral modeling.
Chemical Structure & Pharmacodynamics
3-Me-PCE is an essential subject for those mapping the pharmacological landscape of the arylcyclohexylamine class. Its research profile is defined by its interaction with central excitatory pathways:
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NMDA Receptor Antagonism: 3-Me-PCE acts primarily as a non-competitive NMDA receptor antagonist. Scientists utilize this compound to study the physiological effects of NMDA ion channel blockade on synaptic transmission.
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Monoaminergic Modulation: Structural studies suggest that 3-alkyl substitutions may influence affinity for monoamine transporters. Researchers explore 3-Me-PCE to identify its secondary effects on dopamine and serotonin reuptake.
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Analytical Stability: The powder formulation provides the chemical stability required for long-term storage and the solubility needed for accurate molar dosing in complex experimental protocols.
Primary Research Applications
3-Me-PCE analytical standards are critical for several specialized scientific domains:
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Structure-Activity Relationship (SAR) Mapping: Evaluating how the substitution of a methyl group—rather than a methoxy or hydroxy group—affects the compound’s potency and selectivity for the phencyclidine (PCP) binding site.
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Forensic Toxicology: Developing validated detection methods for LC-MS/MS and GC-MS to differentiate 3-Me-PCE from its isomers in forensic and biological samples.
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Behavioral Pharmacology: Investigating the compound’s impact on locomotor activity, spatial memory, and sensory processing in established research models.
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Metabolic Profiling: Studying the biotransformation of 3-Me-PCE to identify specific metabolites and determine its pharmacokinetic profile compared to parent arylcyclohexylamines.
Technical Specifications
| Feature | Details |
| IUPAC Name | N-ethyl-1-(3-methylphenyl)cyclohexan-1-amine |
| CAS Number | 1354631-78-9 |
| Molecular Formula | $C_{15}H_{23}N$ |
| Molecular Weight | 217.35 g/mol |
| Purity Grade | Analytical Research Grade ($\ge$98%) |
Safety, Regulatory Status, and Procurement
3-Me-PCE is intended strictly for laboratory research and forensic applications. It is not for human or veterinary consumption.
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Regulatory Compliance: Researchers must verify the legal status of 3-Me-PCE within their jurisdiction. It may be subject to restrictive scheduling under “Analogue Acts” in the USA, UK, and various European nations.
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Handling Protocols: Due to its high potency, 3-Me-PCE must be handled in a professional laboratory setting. Use of an analytical balance and appropriate Personal Protective Equipment (PPE) is mandatory.
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Documentation: Every acquisition includes a comprehensive Safety Data Sheet (SDS) detailing chemical stability, solubility, and secure disposal methods.
Why Source Buy 3-Me-PCE Powder Through Verified Channels?
High-stakes research requires materials free from unreacted synthesis precursors and residual solvents. Sourcing through a legitimate research chemical supplier ensures that your 3-Me-PCE powder meets the rigorous analytical requirements necessary for advanced neurological and toxicological investigation.



