Buy MXiPr Powder (Methoxisopropamine) | Analytical Research Profile
Are you investigating the pharmacological impact of $N$-substituted arylcyclohexylamines? MXiPr (Methoxisopropamine), also known as 3-MeO-2′-oxo-PCiPr, is a synthetic research chemical and a structural analogue of Methoxetamine (MXE). It is distinguished by the replacement of the $N$-ethyl group found in MXE with an $N$-isopropyl group. This structural shift is a primary focus for researchers studying how bulky $N$-alkyl substitutions influence receptor binding affinity and metabolic stability.
For research institutions looking to buy research chemicals online, sourcing MXiPr in a high-purity powder form is vital for maintaining the analytical rigor required for in vitro assays and controlled behavioral modeling.
Chemical Structure & Pharmacodynamics
MXiPr is a significant subject within the arylcyclohexylamine class. Its pharmacological profile is defined by its interaction with central excitatory neurotransmission:
-
NMDA Receptor Antagonism: MXiPr acts as a potent non-competitive NMDA receptor antagonist. Researchers investigate its ability to block the ion channel to understand its downstream effects on synaptic plasticity and neurogenesis.
-
Serotonergic Activity: Similar to its parent compound MXE, MXiPr is studied for its potential affinity for the serotonin transporter (SERT). This dual-action mechanism makes it a key subject in research regarding the neurobiology of mood and rapid-acting antidepressant responses.
-
Precision Preparation: The analytical-grade powder formulation ensures rapid solubility in common laboratory buffers, facilitating the exact molar dosing necessary for complex experimental protocols.
Primary Research Applications
MXiPr analytical standards are critical for several specialized scientific domains:
-
Structure-Activity Relationship (SAR) Studies: Analyzing how the $N$-isopropyl group—compared to $N$-ethyl or $N$-methyl groups—affects the compound’s potency and selectivity for the phencyclidine (PCP) binding site.
-
Forensic & Analytical Toxicology: Establishing precise mass spectrometry fragmentation patterns to allow for the definitive identification of MXiPr in biological matrices using LC-MS/MS and GC-MS.
-
Behavioral Pharmacology: Modeling the compound’s impact on cognitive flexibility, locomotor coordination, and sensory gating in established research environments.
-
Pharmacokinetic Profiling: Mapping the metabolic breakdown of $N$-isopropyl substituted arylcyclohexylamines to identify specific biomarkers and clearance rates.
Technical Specifications
| Feature | Details |
| IUPAC Name | 2-(isopropylamino)-2-(3-methoxyphenyl)cyclohexan-1-one |
| CAS Number | 2404245-58-3 |
| Molecular Formula | $C_{16}H_{23}NO_2$ |
| Molecular Weight | 261.36 g/mol |
| Purity Grade | Analytical Research Grade ($\ge$98%) |
Safety, Regulatory Status, and Procurement
MXiPr is intended strictly for laboratory research and forensic applications. It is not for human or veterinary consumption.
-
Regulatory Compliance: Researchers must verify the legal status of MXiPr within their jurisdiction. As a structural analogue of MXE, it may fall under “Analogue Acts” in the USA, or specific controlled substance lists in the UK (PSA 2016) and various European nations.
-
Handling Protocols: Due to its high potency, MXiPr must be handled in a professional laboratory setting. Use of an analytical balance and appropriate Personal Protective Equipment (PPE) is mandatory.
-
Documentation: Every order includes a comprehensive Safety Data Sheet (SDS) detailing chemical stability, toxicity data, and secure disposal protocols.
Why Source Through Verified Channels?
Reliable scientific outcomes depend on the use of research materials free from synthesis byproducts or residual precursors. Sourcing through a legitimate research chemical supplier ensures that your MXiPr powder meets the rigorous purity requirements necessary for high-stakes neurological and toxicological research.



